But the smell dissipates, and for many, it truly helps heal dry skin. However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% ammonium lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. There are, however, no adequate and well-controlled studies in pregnant women. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. * by AmLactin Ammonium Lactate; Third Edition ➺ Ammonium lactate cream is available in 280 grams (two 140 gram… AMMONIUM LACTATE- ammonium lactate lotion  An in vitro study of percutaneous absorption of ammonium lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Other reported clinical experience has not identified differences in responses between elderly and younger patients. Not for Ophthalmic, Oral or Intravaginal Use. Select one or more newsletters to continue. Ammonium lactate is usually applied twice a day. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. ➺ Common brand names: Lac-Hydrin, AmLactin, Geri-Hydrolac, LAClotion, LAC Cream, Al-12 ➺ Generic name: ammonium lactate ➺ Drug class and mechanism: It is an anti-itch prescription medicine. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. Safety and effectiveness of Ammonium Lactate have been demonstrated in infants and children. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% Ammonium Lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Clinical studies of Ammonium Lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% ammonium lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Lac-Hydrin specially formulates 12% lactic acid, neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.4-5.5. Shake well. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. For Dermatologic Use Only This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. CONTAINS: *Ammonium lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Caution is advised when used on the face because of the potential for irritation. Perrigo New York Inc, For Dermatologic Use Only The alpha-hydroxy acids (and their salts) may act as … Other reported clinical experience has not identified differences in responses between elderly and younger patients. Not for Ophthalmic, Oral or Intravaginal Use. Usual Dosage: Shake well. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.5 - 5.5. Shake the lotion form of this medication well just before using it. Use twice daily or as directed by a physician. Use twice daily or as directed by a physician. ➺ It is available in the form of cream as well as lotion. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. Ammonium lactate comes as a cream and a lotion to apply to the skin. Ammonium lactate is an anti- itch topical medication formulated from 12% lactic acid and ammonium hydroxide. The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). It is usually applied to the affected skin area twice daily. ammonium lactate 12 % lotion. August 22, 2012 at 2:36 pm Ammonium lactate is commonly sold over the counter by the name of amlactin, LAC lotion, or LAC hydrin. In general, dose selection for an elderly patient should be cautious. CONTAINS: *Ammonium Lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. This Ammonium Lactate cream infuses skin with moisture and smooths it out to give it a younger and healthier appearance. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. This property may influence hydration of the stratum corneum. Lotions are thinner and lighter in consistency and can be used all over the body (for example, in case of eczema). hydroxyzine, hydrocortisone topical, lidocaine topical, diphenhydramine, Benadryl, Eucerin, Aquaphor, AmLactin, dimethicone topical, CeraVe. No unusual toxic effects were reported. I think soaking is … Keep your skin looking smooth, vibrant and healthy with this Ammonium Lactate 12 Percent Cream. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Clinical studies of ammonium lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Ammonium lactate also prevents keratinization of epidermal skin layer, which keeps skin smoother and hydrated for a longer time. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as Ammonium Lactate to provide a lotion pH of 4.5 - 5.5. The mutagenic potential of Ammonium Lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. In general, dose selection for an elderly patient should be cautious. Ammonium Lactate Lotion 12%C-P , Fliptop - (400grams/14oz) - Pack of 2; Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube by Major Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Not for Ophthalmic, Oral or Intravaginal Use, We comply with the HONcode standard for trustworthy health information -, Lactic Acid and Ammonium Hydroxide Lotion. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. For lot number and expiration date, see bottle. I have been given Lac Hydrin over the years but I hate it because it stings badly if any of your skin is irritated or cracked. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. In dermal Segment I and III studies with ammonium lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Do not use in larger or smaller amounts or for longer than recommended. Use twice daily or as directed by a physician. An in vitro study of percutaneous absorption of Ammonium Lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Usual Dosage: Shake well. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. Available for Android and iOS devices. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. and Milwaukee, Wisconsin A double-blind, paired comparison study was used to evaluate treatment effects of 12% ammonium lactate lotion (Lac-Hydrin) against its … It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Any ammonium lactate lotion will have this smell - I have used several brands with success. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. imprint No data. The oral administration of Ammonium Lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). Safety and effectiveness of ammonium lactate have been demonstrated in infants and children. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. Sadly, a small percentage of you may experience a negative reaction to the lotion. Distributed By Perrigo, Allegan, MI 49010. It is a normal constituent of tissues and blood. … Lactic acid is an alpha-hydroxy acid. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to ammonium lactate formulations. Evaluation of ammonium lactate in the treatment of seborrheic keratoses Maria V. Klaus, MD,a Richard F. Wehr, BS,b Roy S. Rogers III, MD,c Thomas J. Russell, MD: and Lincoln Krochmal, MOb Buffalo, New York, Rochester, Minnesota. In dermal Segment I and III studies with Ammonium Lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. Ammonium Lactate Cream, 12% also contains cetyl alcohol, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. ammonium lactate 12 % topical cream. However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% Ammonium Lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. This is a serious creme that provides incredible relief and promotes healing, but it is not a quick-absorb lotion so one will need gloves to help with absorption. Amlactin Daily Moisturizing Body Lotion 12% at Walgreens. The mechanism(s) by which this is accomplished is not yet known. Apply to the affected areas and rub in thoroughly. There are, however, no adequate and well-controlled studies in pregnant women. Apply to the affected areas and rub in thoroughly. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. For external use only. For external use only. Apply to the affected areas and rub in thoroughly. I've been using it for years, including back when it was only available by prescription here. Apply to the affected areas and rub in thoroughly. Use twice daily or as directed by a physician. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Because many drugs are excreted in human milk, caution should be exercised when Ammonium Lactate is administered to a nursing woman. Get free shipping at $35 and view promotions and reviews for Amlactin Daily Moisturizing Body Lotion 12% Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Shake well. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). Less frequently occurring side effects include irritation, dryness, eczema, changes in skin color, or small … No unusual toxic effects were reported. Last updated on Sep 21, 2020. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to Ammonium Lactate formulations. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. The oral administration of ammonium lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. Ammonium lactate hydrates the outermost skin layer and promotes skin moisturizing for a prolonged time. For lot number and expiration date, see bottle. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The mutagenic potential of ammonium lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. It is a moisturizer that is designed to treat the symptoms of dry, scaly skin conditions such as ichthyosis vulgaris and xerosis. Caution is advised when used on the face because of the potential for irritation. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Because many drugs are excreted in human milk, caution should be exercised when ammonium lactate is administered to a nursing woman. Set id: dc3a6462-0f2c-4306-b5ef-c7b47395e959, Not for Ophthalmic, Oral or Intravaginal Use, 225 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product, 400 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product. Apply ammonium lactate at around the same time (s) every day. Medically reviewed by Drugs.com. This property may influence hydration of the stratum corneum. The most frequent side effect of using topical 12 percent ammonium lactate lotion is a stinging or burning sensation. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. Distributed By Perrigo, Allegan, MI 49010. The mechanism(s) by which this is accomplished is not yet known. Use exactly as directed on the label, or as prescribed by your doctor. color white shape No data. Rash and peeling skin may also occur. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Many lotions and creams sting terribly and cause worse suffering, but Ammonium Lactate cream is so cooling and soothing and does not further irritate my sensitive skin. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). I use it on hands, feet, knees. This medicine is a white, lotion ‹ Back to Gallery. * by AmLactin Ammonium Lactate… This topical medication is made from 12% lactic acid and ammonium hydroxide.